In this US TV mini-series, Los Angeles is gripped in panic as an unknown virus threatens the population. When an inbound jet from Australia reports the death of a teenager from raging fever and convulsions, Los Angeles airport is put into quarantine, much to the annoyance of Mayor Richard Delasandro (Eric Roberts). But as the virus rapidly spreads to other areas of the city, Center for Disease Control epidemiologist Dr. Kayla Martin (Tiffani Thiessen) quickly realises the potential for disaster, and sets out on the hunt for the outbreak's source, a journey that will take her on a frantic race across continents with time running out.